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Cat. No. Product Name Information
PC-49187

GLPG2451

GLPG2451 (GLPG 2451) is a potent potentiator of cystic fibrosis transmembrane conductance regulator (CFTR) with EC50 of 11 nM for F508del CFTR in the YHA assay and EC50 of 18 nM in TECC assay using HBE cells from patients carrying the F508del mutation.
PC-72975

Bamocaftor

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.
PC-72974

Bamocaftor potassium

Bamocaftor (VX-659) is a next-generation CFTR corrector, restores F508del-CFTR protein function.
PC-38208

ARN23765

ARN23765 (ARN 23765) is a highly potent, pharmacological corrector of the mutant CFTR chloride channel with EC50 of 38 pM in cellular assays.
PC-60232

GLPG-1837

A potent, orally available CFTR potentiator with EC50 of 3 nM and 339 nM on F508del and G551D CFTR, respectively.
PC-60231

GLPG-2222

GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.
PC-20491

VX-661

Tezacaftor (VX-661) is a broad-acting CFTR corrector that facilitates the cellular processing and trafficking of normal CFTR and multiple mutant CFTR forms, including F508del, thereby increasing the amount of CFTR protein at the cell surface, resulting in increased chloride transport.

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