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Cat. No. Product Name Information
PC-49532

BRD7586

SpCas9 inhibitor

BRD7586 (BRD 7586) is a potent, cell-permeable small-molecule inhibitor of SpCas9 with Kd value of 0.52 uM.
PC-23746

BRD0539

SpCas9 inhibitor

BRD0539 is a cell-permeable, reversible inhibitor of Streptococcus pyogenes Cas9 (SpCas9) with IC50 of 22 uM in vitro DNA cleavage assays, effectively inhibits the DNA-binding ability of SpCas9 by disrupting the interaction between SpCas9 and the protospacer adjacent motif (PAM).

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