| Cat. No. |
Product Name |
Information |
| PC-35260 |
GSK3004774
|
GSK3004774 (GSK-3004774) is a potent, nonabsorbable, gastrointestinally-restricted agonist agonist of calcium-sensing receptor (CaSR) with pEC50 of 7.3. |
| PC-63560 |
Velcalcetide
|
Velcalcetide (AMG-416, Velcalcetide, Etelcalcetide, KAI-4169) is a potent, peptide agonist of CaSR, dose-dependenty increases IP1 accumulation with EC50 of 25 uM in cell based assays. |
| PC-61402 |
Upacicalcet
|
Upacicalcet is a novel positive allosteric modulator of the calcium-sensing receptor (CaSR), a novel secondary hyperparathyroidism drug that targets the amino acid binding site of CaSR. |
| PC-20137 |
(S)-AC-265347
|
(S)-AC-265347 is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), 10- to 20-fold more potent than (R)-AC-265347. |
| PC-20136 |
AC26534
|
AC-265347 (AC265347) is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), activates CaSR signaling in cellular proliferation and phosphatidylinositol (PI) hydrolysis assays with potencies of 30 and 10 nM, respectively. |
| PC-62910 |
Calindol hydrochloride
|
Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+). |
| PC-62909 |
Tecalcet
|
Tecalcet (R-568. |
