| Cat. No. |
Product Name |
Information |
| PC-72647 |
Multikinase inhibitor 108600
|
Multikinase inhibitor 108600 (108600) is a novel multi-kinase inhibitor and inhibitor of TNBC growth (GI50=0.12-0.75 uM), inhibits CK2α1/α2, DYRK1A, 1B, and DYRK2 and TNIK (IC50=5-50 nM). |
| PC-60582 |
(R)-DRF053 dihydrochloride
|
(R)-DRF053 dihydrochloride (DRF053) is a potent, cell-permeable, dual CK1/CDK inhibitor with IC50 of 14 nM, 220 nM and 80 nM for CK1, CDK5/p25 and CDK1/cyclin B, respectively. |
| PC-60581 |
Bischof-5
|
Bischof-5 (CK1δ inhibitor 5) is a potent, specific casein kinase 1δ (CK1δ) inhibitor with IC50 of 40 nM. |
| PC-60580 |
SR-2890
|
SR-2890 is a potent, highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 of 4 nM for CK1δ. |
| PC-60387 |
SSTC3
|
SSTC3 is a novel small-molecule CK1α activator with EC50 of 30 nM (WNT-driven reporter gene assay), Kd of 32 nM. |
| PC-60385 |
VU-WS113
|
VU-WS113 is a potent inhibitor of Wnt signaling with EC50 of 80 nM that selectively potentiates CK1α kinase activity. |
| PC-45871 |
CX-4945 sodium salt
|
CX-4945 sodium salt (Silmitasertib) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase CK2 with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
