| Cat. No. |
Product Name |
Information |
| PC-35362 |
BAY-524
|
BAY-524 (BAY524) is a potent, selective, ATP-competitive inhibitor of Bub1 kinase with IC50 of 450 nM. |
| PC-63128 |
BAY-1816032
|
BAY-1816032 (BAY1816032) is a highly potent, selective, orally active BUB1 mitotic checkpoint serine/threonine kinase with IC50 of 7 nM, displays excellent selectivity on a panel of 395 kinases. |
| PC-60310 |
GNE-900
|
GNE-900 (GNE900) is a potent, selective, ATP-competitive, and orally bioavailable Chk1 inhibitor with IC50 of <1 nM. |
| PC-60285 |
XL-844
|
XL-844 (EXEL9844) is a potent, specific, orally available, ATP‑competitive inhibitor of Chk1 and Chk2 with Ki of 2.2 nM and 0.07 nM, respectively. |
| PC-60276 |
GDC-0575
|
GDC-0575 (ARRY-575, RG-7741) is a potent, selective and orally bioavailable Chk1 inhibitor with IC50 of 1.2 nM. |
| PC-45427 |
Prexasertib
|
Prexasertib (LY-2606368) is a potent, selective, ATP-competitive inhibitor of CHK1 with Ki of 0.9 nM. |
| PC-42769 |
AZD-7762
|
AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM. |
