| Cat. No. |
Product Name |
Information |
| PC-21255 |
ZK756326
CCR8 agonist
|
ZK 756326 is a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8, inhibits the binding of the CCR8 ligand I-309 (CCL1) with IC50 of 1.8 uM. |
| PC-20733 |
AMG487
CXCR3 antagonist
|
AMG487 (AMG 487, VUF10085) is a potent and selective orally bioavailable chemokine (C-X-C motif) receptor 3 (CXCR3) antagonist with IC50 of 8 nM for inhibiting 125I-IP-10 binding. |
| PC-20372 |
IPG7236
CCR8 inhibitor
|
IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM. |
| PC-20291 |
NUCC-390 dihydrochloride
CXCR4 agonist
|
NUCC-390 dihydrochloride (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
| PC-20290 |
NUCC-390
CXCR4 agonist
|
NUCC-390 (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
| PC-20096 |
ACT-777991
CXCR3 inhibitor
|
ACT-777991 (ACT777991) is a highly potent and selective CXCR3 antagonist with IC50 of 33 nM. |
| PC-49866 |
RIST4721
CXCR2 inhibitor
|
RIST 4721 (Vimnerixin, AZD 4721) is a potent, specific and orally active antagonist of CXCR2, potently inhibits neutrophil chemotaxis with IC50 of 17 nM. |
| PC-49464 |
RPT193
CCR4 inhibitor
|
RPT193 (RPT-193) is a highly potent, selective and orally active CCR4 antagonist, inhibits CCL22- induces human Th2 chemotaxis with IC50 of 370 nM. |
| PC-49368 |
LN6023
ACKR3 agonist
|
LN6023 (LN-6023) is a potent, selective and first-in-class agonist of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.5 uM. |
| PC-49306 |
MR120
CCR6 inhibitor
|
MR120 (CCR6 antagonist 1b) is a potent, selective CCR6 antagonist, disrupts the CCL20-induced chemotaxis of CCR6+CD4+ T cells. |
| PC-49265 |
ACT-660602
CXCR3 antagonist
|
ACT-660602 (ACT660602) is a potent, selective and orally bioavailable CXCR3 antagonist with IC50 of 204 nM in human blood. |
| PC-49264 |
ACT-672125
CXCR3 antagonist
|
ACT-672125 (ACT672125) is a potent, selective CXCR3 antagonist with IC50 of 239 nM in human blood. |
