| Cat. No. |
Product Name |
Information |
| PC-49192 |
TMEM16A blocker 1PBC
|
1PBC is a small molecule blocker of calcium-activated chloride channel TMEM16A, blocks TMEM16A completely with an IC50 of 4 uM at zero mV and saturating Ca2+ concentration (2 uM). |
| PC-38752 |
DRAinh-A270
|
DRAinh-A270 is a small-molecule, selective inhibitor of intestinal anion exchanger SLC26A3 (DRA), inhibits SLC26A3-mediated chloride/bicarbonate exchange with IC50 of 35 nM and oxalate/chloride exchange with IC50 of 60 nM. |
| PC-35990 |
T16Ainh-A01
|
T16Ainh-A01 is an inhibitor of the calcium-activated chloride channel TMEM16A, inhibits Ca2+-activated Cl− channel (CACC) activity in TMEM16A-transfected FRT cells with IC50 of 1 uM. |
| PC-35541 |
DRAinh-A250
|
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
| PC-62063 |
VU 0463271
|
VU 0463271 is a potent, selecitve inhibitor of the neuronal K-Cl cotransporter KCC2 with IC50 of 61 nM. |
| PC-60024 |
CLP257
|
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM. |
| PC-20364 |
Ani9
|
Ani9 is a potent, selective anoctamin1 (ANO1, TMEM16A) channel inhibitor with IC50 of 107 nM, with negligible effect on ANO2 (IC50>10 uM). |
