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Cat. No. Product Name Information
PC-38846

W54011

W-54011 (W54011) is a potent, selective, orally active and non-peptide C5a receptor antagonist, inhibits the binding of 125I-labeled C5a to human neutrophils with Ki of 2.2 nM.
PC-73000

C5 complement inhibitor 7

C5 complement inhibitor 7 (C5-IN-7) is a potent, small-molecule inhibitor of C5 complement protein with serum assay IC50 of <5 nM (2% human serum complement inhibition).
PC-72006

C3aR antagonist JR14a

C3aR antagonist JR14a is a potent and selective antagonist of human Complement C3a receptor (hC3aR) with IC50 of 10 nM (Inhibition of intracellular Ca2+ release induced by 100 nM C3a).
PC-72001

JPE1375

JPE1375 is a potent, peptidomimetic C5a receptor antagonist with IC50 of 39 nM, inhibits neutrophil influx in the RPAR in mice.
PC-72000

BM213

BM213 (BM-213) is a potent, selective and stable peptide C5aR1 agonist with EC50 of 59 nM.
PC-38339

DF2593A

DF2593A (DF 2593A) is a potent, selective, noncompetitive allosteric inhibitor of C5aR with IC50 of 5 nM (C5a-induced human PMN migration inhibition), and rat and mouse orthologs (IC50=6.0 nM and IC50=1.0 nM, respectively).
PC-38338

DF3016A

DF3016A (DF 3016A) is a potent and selective C5aR inhibitor with IC50 of 50 nM (C5a-induced human PMN migration and IC50 of 45 and 37 nM against rat and mouse C5aR, respectively.

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