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Cat. No. Product Name Information
PC-49111

SU0448

SU0448 is a specific, cell-permeable small molecule activator of the DNA repair enzyme Human MutT Homolog 1 (MTH1) with AC50 value of 5.5 uM, inhibits cell viability of HCC1806 cells with IC50 of 36.1 uM.
PC-72920

T2AA

T2AA (T2 amino alcohol) is a small molecule proliferating cell nuclear antigen (PCNA) inhibitor, inhibits interaction of PCNA/PIP-box peptide with IC50 of 1 uM.
PC-35301

AOH1160

AOH1160 (AOH-1160) is a potent, first-in-class, orally available small molecule inhibitor of Proliferating cell nuclear antigen (PCNA).
PC-63192

IACS-4619

IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM.
PC-62706

Karonudib

Karonudib (TH1579) is an analogue of TH588, a potent, selective MTH1 inhibitor with good oral availability and demonstrates excellent pharmacokinetic and anti-cancer properties in vivo..
PC-62705

IACS-4759

IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.6 nM.
PC-62517

TH 5427

TH 5427 (TH5427) is a potent, small molecule NUDT5 (NUDIX5) inhibitor with IC50 of 29 nM, 690-fold selectivity for NUDT5 over MTH1 (NUDT1) in vitro.

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