| Cat. No. |
Product Name |
Information |
| PC-49309 |
RBF197
|
RBF197 (RBF-197) is a novel highly potent and selective eIF4A inhibitor, inhibits human eIF4A helicase activity with IC50 of 55.2 pM. |
| PC-49308 |
eIF4A inhibitor 28
|
eIF4A inhibitor 28 (eIF4A-IN-28) is a novel small molecule RNA-competitive, ATP-uncompetitive inhibitor of eIF4A, inhibits eIF4A ATPase and helicase activities with IC50 of 8.6 and 6.6 uM, respectively. |
| PC-72234 |
EGPI-1
|
EGPI-1 is a potent small molecule that inhibits the translation initiation factors eIF4E/eIF4G interaction. |
| PC-36005 |
2BAct
|
2BAct (eIF2B activator 2BAct) is a novel, highly selective, CNS-permeable small molecule eIF2B activator with EC50 of 33 nM in cell-based reporter assays. |
| PC-35083 |
Metarrestin
|
Metarrestin (ML246) is a specific inhibitor of perinuclear compartment (PNC), disrupts PNCs in PC3M-GFP-PTB cells with IC50 of 0.39 uM, specifically binds eEF1A2. |
| PC-63308 |
eFT226
|
eFT226 is a novel, potent and selective eIF4A inhibitor with anti-tumor activity in B-cell malignancies, promotes eIF4A binding to specific mRNA sequences and interferes with the assembly of the eIF4F initiation complex. |
| PC-61019 |
eIF4A3 inhibitor 53a
|
eIF4A3 inhibitor 53a is a potent, selective and cell-active eukaryotic initiation factor 4A3 (eIF4A3) inhibitor with IC50 of 0.26 uM, SPR Kd of 43 nM. |
