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Request The Product List ofFarnesoid X Receptor (FXR) Farnesoid X Receptor (FXR)

Cat. No. Product Name Information
PC-38044

EDP-305

EDP-305 (EDP305) is a potent, selective, nonbile acid farnesoid X receptor (FXR) agonist with antifibrotic effect.
PC-61390

Nidufexor

Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders.
PC-61368

Cilofexor

Cilofexor (GS-9674, GS9674, PX-104) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.
PC-61057

DM509

DM509 is a potent, orally active dual modulator of FXR and soluble epoxide hydrolase (sEH) that exertss partial FXR agonism (pEC50=7.7) and sEH inhibitory activity (pIC50=8.4).
PC-60080

GSK-2324

GSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay.
PC-60079

LY-2562175

LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM.
PC-60056

Tropifexor

Tropifexor (LJN-452, LJN452) is a novel highly potent, selective, orally acitive FXR full agonist with EC50 of 0.26 nM.

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