| Cat. No. |
Product Name |
Information |
| PC-38044 |
EDP-305
|
EDP-305 (EDP305) is a potent, selective, nonbile acid farnesoid X receptor (FXR) agonist with antifibrotic effect. |
| PC-61390 |
Nidufexor
|
Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders. |
| PC-61368 |
Cilofexor
|
Cilofexor (GS-9674, GS9674, PX-104) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models. |
| PC-60080 |
GSK-2324
|
GSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay. |
| PC-60079 |
LY-2562175
|
LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM. |
| PC-60056 |
Tropifexor
|
Tropifexor (LJN-452, LJN452) is a novel highly potent, selective, orally acitive FXR full agonist with EC50 of 0.26 nM. |
| PC-45825 |
GW-4064
|
GW-4064 (GW4064) is a potent and selective FXR agonist with EC50 of 15 nM in cell-free assay, >200-fold more potent than CDCA. |
