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Cat. No. Product Name Information
PC-20789

Erg6 inhibitor H55

Fungal Erg6 inhibitor

Erg6 inhibitor H55 is an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase (Erg6), potently inhibits C. albicans hyphal formation in multiple cultural conditions.
PC-72457

Azoffluxin

Cdr1 inhibitor

Azoffluxin (CMLD012336) is a bis-benzodioxolylindolinone that synergizes with fluconazole against C. auris through the inhibition of efflux pump Cdr1, thus increasing intracellular fluconazole levels.
PC-63228

ML316

Mir1 inhibitor

ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1, exhibits potent antifungal activity against the moderatelyazole-resistant C. albicans strain CaCi-2 with MIC of 0.05 ug/ml.
PC-63050

Butenafine hydrochloride

Butenafine is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
PC-62617

APX001

APX001 (Fosmanogepix, E1210) is a novel broad-spectrum antifungal agent that inhibits the fungal protein Gwt1, demonstrates significantly acitive MIC50 and MIC90 values of 0.004 and 0.031 ug/ml (16 strains of C. auris).
PC-62615

PC945

Opelconazole (PC945) is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively.
PC-62607

PC1244

Fungal CYP51A/CYP51B inhibitor

PC1244 is a long acting fungicidal azole that targets A. fumigatus CYP51A and CYP51B, inhibits ergosterol synthesis in A. fumigatus with IC50 of 8 nM.
PC-61753

VT-1161

Fungal CYP51 inhibitor

VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
PC-61752

VT-1598

Fungal CYP51B inhibitor

VT-1598 is a potent, high-affinity, oral inhibitor of fungal sterol 14α-demethylase (CYP51B) with Kd of 13 nM.
PC-70346

Filastatin

Antifungal

Filastatin is a small molecule inhibitor that inhibits adhesion of C. albicans to polystyrene.
PC-70224

F-901318

Fungal DHODH inhibitor

F-901318 (Olorofim) is a novel antifungal agent that inhibits A. fumigatus DHODH with IC50 of 44 nM.
PC-60411

SCY-078

Ibrexafungerp (MK 3118, SCY-078) is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml).

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