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Cat. No. Product Name Information
PC-21852

NP-BTA

C. albicans Gln4 inhibitor

NP-BTA is a potent, allosteric inhibitor of C. albicans glutaminyl-tRNA synthetase Gln4 with ITC KD of 180 nM and IC50 of 108 nM, strongly inhibits Candida albicans growth.
PC-20789

Erg6 inhibitor H55

Fungal Erg6 inhibitor

Erg6 inhibitor H55 is an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase (Erg6), potently inhibits C. albicans hyphal formation in multiple cultural conditions.
PC-49414

MMV688766

Antifungal

MMV688766 (MMV 688766) is a small molecule displaying broad-spectrum fungicidal activity through perturbation of lipid homeostasis, inhibits the growth of four geographically distinct C. auris clades with MIC80 of 12.5-50 uM.
PC-38699

YU385599

Fungal PanK inhibitor

YU385599 is a potent small molecule inhibitor of fungal pantothenate kinase (PanK) with Ki of 106 nM (A. fumigatus AfPanK), also inhibits S. cerevisiae Cab1 enzyme with Ki of 170 nM, inhibits the growth of several Candida species.
PC-38447

Fluxapyroxad

Succinate dehydrogenase inhibitor

Fluxapyroxad is a new generation carboxamide funugicide and succinate dehydrogenase (Sdh) inhibitor, exhibits antifungal activities against R. solani with EC50 of 0.033 mg/mL.
PC-73393

1-ECBC

Yak1 inhibitor

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
PC-73392

1-ABC

Yak1 inhibitor

1-ABC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
PC-72457

Azoffluxin

Cdr1 inhibitor

Azoffluxin (CMLD012336) is a bis-benzodioxolylindolinone that synergizes with fluconazole against C. auris through the inhibition of efflux pump Cdr1, thus increasing intracellular fluconazole levels.
PC-72423

GW461484A

Yck2 inhibitor

GW461484A (GW-461484A) is a potent small molecule capable of restoring caspofungin sensitivity, inhibits Yck2 kinase in C. albicans, originally discovered as an inhibitor of human p38α with IC50 of 150 nM.
PC-38031

Rezafungin

Antifungal

Rezafungin (CD101) is a long-acting novel echinocandin possesses potent antibiofilm activity against early and mature candida albicans biofilms.
PC-38016

Echinocandin B

Echinocandin B is a cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus nidulans var. echinulatus with specific anti-yeast activity.
PC-35452

Fosmanogepix

Fosmanogepix (APX001 prodrug) is a novel antifungal agent, the prodrug form of APX001, which inhibits the fungal protein Gwt1..

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