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Cat. No. Product Name Information
PC-63228

ML316

ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1, exhibits potent antifungal activity against the moderatelyazole-resistant C. albicans strain CaCi-2 with MIC of 0.05 ug/ml.
PC-63050

Butenafine hydrochloride

Butenafine is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
PC-62617

APX001

APX001 (Fosmanogepix, E1210) is a novel broad-spectrum antifungal agent that inhibits the fungal protein Gwt1, demonstrates significantly acitive MIC50 and MIC90 values of 0.004 and 0.031 ug/ml (16 strains of C. auris).
PC-62615

PC945

Opelconazole (PC945) is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively.
PC-70224

F-901318

F-901318 (Olorofim) is a novel antifungal agent that inhibits A. fumigatus DHODH with IC50 of 44 nM.
PC-60411

SCY-078

Ibrexafungerp (MK 3118, SCY-078) is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml).
PC-20807

HLQ2H

HLQ2H (Msi3 inhibitor 2H) is a first-in-class, specific inhibitor of fungal Hsp110 molecular chaperone Msi3, inhibits the holdase activity of Msi3 (IC50=5.02 uM) as well as the growth and viability of C. albicans.

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