| Cat. No. |
Product Name |
Information |
| PC-47098 |
ASP8062
|
ASP8062 is a potent, selective GABA B receptor positive allosteric modulator (PAM), positive allosteric modulating activity for human and rat GABAB receptors, exerts analgesic effects in rat model of fibromyalgia. |
| PC-38319 |
Zuranolone
|
Zuranolone (SAGE-217) is an orally active, positive allosteric modulator of the GABAA receptor with EC50 of 375/299 nM (α1β2γ2/α4β3δ). |
| PC-35483 |
KRM-II-81
|
KRM-II-81 is a selective α2/α3 subtype GABAA receptor ligand (positive allosteric modulator) with EC50 of 937 nM for α3β3γ2 GABAAR. |
| PC-63442 |
ONO-8590580
|
ONO-8590580 is a novel potent, selective GABAA α5 negative allosteric modulator, binds to the benzodiazepine binding sites on recombinant human α5-containing GABAA receptors with Ki of 7.9 nM. |
| PC-62770 |
MRK-623
|
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist.. |
| PC-62098 |
LAU159
|
LAU159 is a potent, functionally selective positive modulator of α6β3γ2 GABAA receptor.. |
| PC-62089 |
PF-06372865
|
PF-06372865 (Darigabat) is a novel potent, α2/3 functionally selective GABAA receptor positive allosteric modulator. |
