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Cat. No. Product Name Information
PC-72725

COB-187

COB-187 (COB187) is a highly potent and selective inhibitor of GSK-3 with IC50 of 22/11 nM against GSK-3α/GSK-3β.
PC-63311

BRD0705

BRD0705 is a potent, paralog-selective GSK3α inhibitor with IC50 of 66 nM, 8-fold selectivity over GSK3β (IC50=515 nM).
PC-63153

1-Azakenpaullone

1-Azakenpaullone is an analog of kenpaullone and is a potent, selective GSK3β inhibitor with IC50 of 18 nM, weakly inhibits CDK1/cyclin B and CDK5/p25 (IC50=2.0 and 4.2 uM).
PC-60431

9-ING-41

Elraglusib (9-ING-41) is a novel potent, selective GSK-3β inhibitor with IC50 of 0.7 uM.
PC-42428

CHIR-99021

Laduviglusib (CHIR-99021, CT99021) is a potent, specific GSK-3 inhibitor with IC50 of 5 nM and 10 nM for GSK3β and GSK3α, respectively.
PC-42628

AR-A014418

AR-A014418 is a potent, specific ATP-competitive inhibitor of GSK-3β with Ki/IC50 of 38/104 nM.
PC-45724

Indirubin-3|-monoxime

A potent GSK3β inhibitor with IC50 of 22 nM.

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