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Cat. No. Product Name Information
PC-20678

AB-836

HBV capsid inhibitor

AB-836 is a next generation oral hepatitis B virus (HBV) capsid inhibitor with HepDE19 EC50 of 10 nM, interacts with HBV core protein and demonstrates robust antiviral activity.
PC-20253

Bersacapavir

HBV capsid inhibitor

Bersacapavir (JNJ 56136379, JNJ-6379) is a potent HBV capsid assembly modulator, JNJ-6379 specifically and potently inhibits HBV replication with EC50 of 54 nM (HepG2.117 cells).
PC-20252

Bulevirtide

HBV entry inhibitor

Bulevirtide (Myrcludex B, MyrB) is an acylated peptide derived from the large HBV envelope protein, inhibits virus entry and infection.
PC-20059

Neracorvir

HBV inhibitor

Neracorvir is a potent anti-HBV agent, targets HBV surface antigen.
PC-49649

E-CFCP

HBV inhibitor

E-CFCP is a novel long-acting nucleotide reverse transcriptase inhibitor (NRTI) against HBV, shows potent activity against HBV WTD1 and HBV WTC2 with IC50 of 1.8 and 0.7 nM, respectively.
PC-49567

Vebicorvir

HBV inhibitor

Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor, exhibits selective inhibition of HBV DNA replication with EC50 from 173 nM to 307 nM.
PC-49553

Nitazoxanide

HBx-DDB1 inhibitor

Nitazoxanide (NTX) is a thiazolide anti-infective agent that efficiently inhibits the HBV regulatory protein X (HBx)-DDB1 protein interaction, exhibits potent inhibition of both HBV and HCV replication.
PC-49333

GST-HG121

HBV antigen inhibitor

GST-HG131 is a specific small molecule HBV antigen inhibitor, exhibits excellent and specific HBV antigens inhibition with EC50 of 28.2 nM (HBsAg) and 16.0 nM (HBeAg), respectively.
PC-47007

DF-006

ALPK1 agonist

DF-006 is a small molecule, orally active Alpha-kinase 1 (ALPK1) agonist, activates ALPK1 and stimulates host innate immunity locally in liver, DF-006 enacts potent anti-HBV responses in mouse models of HBV and in primary human hepatocytes.
PC-38680

Firzacorvir

HBV inhibitor

Firzacorvir (ABI-H2158) is a novel potent HBV core inhibitor structurally distinct from other core inhibitors, ABI-H2158 is a pan-genotypic HBV inhibitor with EC50s ranging from 7.1 to 22 nM across HBV genotypes A-E.
PC-38657

ZINC20451377

HBsAg inhibitor

ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) with high affinity (Kd=65.3 nM), reduces HBsAg levels and HBV virion secretion in cell culture model for HBV.
PC-38561

ATI-2173

HBV inhibitor

ATI-2173 is a novel liver-targeted prodrug of clevudine, ATI-2173 is a selective inhibitor of HBV with EC50 of 1.31 nM in primary human hepatocytes with minimal to no toxicity.

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