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Cat. No. Product Name Information
PC-21408

NT160

class IIa HDAC inhibitor

NT160 is a high affinity, selective class-IIa histone deacetylase (HDAC) inhibitor with IC50 of 80 nM (HDAC4), 600-fold selectivity over HDAC2 and 27-fold selectivity over HDAC8.
PC-21407

YAK540

class IIa HDAC inhibitor

YAK540 is a potent, highly selective class IIa HDAC inhibitor with IC50 of 114 nM (HDAC4), displays excellent selectivity against HDAC2 (265-fold), HDAC6 (100-fold), and HDAC8 (82-fold).
PC-20992

Yanostat

class I HDAC inhibitor

Yanostat (KH16) is a novel potent HDAC inhibitor with low nanomolar in vitro activity against class I HDACs (HDAC1/2/3 IC50=13/34/6 nM).
PC-20984

Citarinostat

HDAC6 inhibitor

Carinostat (ACY-241) is a second generation potent, orally active and high-selective HDAC6 inhibitor with IC50 of 2.6 nM.
PC-20913

Givinostat hydrochloride monohydrate

pan HDAC inhibitor

Givinostat (ITF-2357) is a potent, orally active, pan-HDAC inhibitor with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.
PC-20784

Romidepsin

class I HDAC inhibitor

Romidepsin (FK228, NSC 63017, R 901228, Depsipeptide) is a natrual produrct from Chromobacterium violaceum as class I HDACs inhibitor, inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1400 nM, respectively.
PC-20479

Purinostat

Class I /IIb HDAC inhibitor

Purinostat is a potent, highly selective class I and IIb HDAC inhibitor with IC50 of 0.81, 1.4, 1.7, and 3.8 nM for class I HDAC1, 2, 3, and 8, and 11.5, 1.1 nM for class IIb HDAC 6 and 10, respectively.
PC-20402

SBI-46

HDAC inhibitor

SBI-46 (SBI 46) is an antiandrogen-equipped histone deacetylase (HDAC) inhibitor, strongly binds to androgen receptor (AR, IC50=8.4 nM) and potently inhibited HDACs and the proliferation of AR+ CRPC.
PC-20239

HO53

HDAC3 inhibitor

HO53 is a small moecule inducer of cathelicidin antimicrobial peptide gene (CAMP) expression in bronchial epithelium cells, HO53 is a histone deacetylase (HDAC) inhibitor, interacts directly with HDAC3.
PC-20238

RGFP963

HDAC3 inhibitor

RGFP963 (RGFP 963) is a potent, selective class I HDAC inhibitor with IC50 of 1.51 uM, 0.75 and 0.096 uM for HDAC1, HDAC2, and HDAC3, respectively.
PC-20237

RGFP966

HDAC3 inhibitor

RGFP966 (RGFP 966) is a potent, specific HDAC3 inhibitor with IC50 of 0.08 uM, without effective inhibition of any other HDACs at 15 uM.
PC-20197

TTA03-107

HDAC1 inhibitor

TTA03-107 is a potent, selective HDAC1 inhibitor with Ki of 3.22 and 17.6 nM for HDAC1/2, respectively.

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