| Cat. No. |
Product Name |
Information |
| PC-49514 |
TBA-7371
|
TBA-7371 (TBA7371, AZ 7371) is a potent, non-covalent inhibitor of decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) with IC50 of 10 nM, an enzyme involved in mycobacterial cell wall biogenesis. |
| PC-49168 |
PAV-206
|
PAV-206 is a novel potent antiretroviral chemotype that inhibits HIV-1 replication with EC50 of 34 nM in HIV-1-infected MT-2 T cells, and 75 nM in HIV-1-infected peripheral blood mononuclear cells (PBMCs), inhibits HIV-1 replication by interfering with HIV-1 assembly. |
| PC-49139 |
RO-0335
|
RO-0335 is a highly potent, selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with IC50 of 8.1 nM, potently inhibits HIV replication with IC50 of 1.3 nM in cell based assays. |
| PC-38563 |
Temsavir
|
Temsavir (BMS-626529) is a highly potent, small molecule HIV-1 attachment inhibitor with IC50 values of 2.26 nM, 0.34 nM and 1.3 nM for HIV-1 subtype A, B, and C envelope, repectively. |
| PC-73436 |
Pirmitegravir
|
Pirmitegravir is a highly potent, first-in-class, allosteric HIV-1 integrase inhibitor (ALLINI), targets LEDGF/p75 binding site, displays picomolar IC50 antiviral potency in human PBMCs. |
| PC-73248 |
FD028
|
FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41. |
| PC-72683 |
GSK3739936
|
GSK3739936 (BMS-986180) is a potent, allosteric HIV-1 integrase (ALLINI), shows excellent potency in vitro against majority of the 124/125 variants (EC50=1.7 nM). |
