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Cat. No. Product Name Information
PC-20807

HLQ2H

HLQ2H (Msi3 inhibitor 2H) is a first-in-class, specific inhibitor of fungal Hsp110 molecular chaperone Msi3, inhibits the holdase activity of Msi3 (IC50=5.02 uM) as well as the growth and viability of C. albicans.
PC-49317

PLTFBH

PLTFBH is a cell-active small molecule inhibitor of DNAJA1, binds to and reduces protein levels of DNAJA1 and several other HSP40/J-domain proteins (JDPs), specifically reduces conformational mutp53 levels similar to PLIHZ.
PC-73319

CCT361814

CCT361814 (NXP800) is a potent, selective and orally bioavailable inhibitor of HSF1 pathway with IC50 of 94 nM (SK-OV-3, HSP72 cell-based ELISA).
PC-73076

DDO-5936

DDO-5936 (DDO5936) is a cell-active, specidic small-molecule inhibitor of Hsp90-Cdc37 protein-protein interaction (PPI) without ATPase inhibition, binds to Hsp 90 with Kd of 3.86 uM.
PC-73010

Foldamer 33

Foldamer 33 is a small molecule HSP110 inhibitor, directly binds to the nucleotide-binding domain (NBD) of HSP110, blocks HSP110 chaperone function and colorectal cancer growth.
PC-72711

PU-HZ151

PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays.
PC-72710

PU-H71

PU-H71 (Zelavespib, NSC 750424) is a potent and selective inhibitor of Hsp90 (Heat shock protein 90) with IC50 of 51 nM in MDA-MB-468 cells.

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