| Cat. No. |
Product Name |
Information |
| PC-73319 |
CCT361814
|
CCT361814 (NXP800) is a potent, selective and orally bioavailable inhibitor of HSF1 pathway with IC50 of 94 nM (SK-OV-3, HSP72 cell-based ELISA). |
| PC-73076 |
DDO-5936
|
DDO-5936 (DDO5936) is a cell-active, specidic small-molecule inhibitor of Hsp90-Cdc37 protein-protein interaction (PPI) without ATPase inhibition, binds to Hsp 90 with Kd of 3.86 uM. |
| PC-73010 |
Foldamer 33
|
Foldamer 33 is a small molecule HSP110 inhibitor, directly binds to the nucleotide-binding domain (NBD) of HSP110, blocks HSP110 chaperone function and colorectal cancer growth. |
| PC-72711 |
PU-HZ151
|
PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays. |
| PC-72710 |
PU-H71
|
PU-H71 (Zelavespib, NSC 750424) is a potent and selective inhibitor of Hsp90 (Heat shock protein 90) with IC50 of 51 nM in MDA-MB-468 cells. |
| PC-72704 |
AIMP2-DX2 inhibitor 1
|
AIMP2-DX2 inhibitor 1 (Compound 1) is a specific chemical probe that can inhibit the tumor-promoting interaction between AIMP2-DX2 and HSP70 (IC50=2.9 uM). |
| PC-72659 |
Bufalin
|
Bufalin is a highly toxic, effective anti-cancer compound, targets Hsp90 cochaperone AHSA1 (Aha1, Activator of HSP90 ATPase Activity 1). |
