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Cat. No. Product Name Information
PC-61482

TAI-95

TAI-95 (T-1101, TAI 95) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
PC-61480

INH154

INH154 is a novel small molecules disrupting Hec1/Nek2 interaction, inhibits HeLa and MDA-MB-468 cancer cells growth with IC50 of 0.20 and 0.12 uM, respectively.
PC-42194

INH-6

A small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively.
PC-20311

Nek2 inhibitor 66

Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM.
PC-20310

T-1101 tosylate

T-1101 tosylate (TAI-95 tosylate) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
PC-20309

JH295

JH295 (JH-295) is a potent, selective and irreversible Nek2 kinase inhibitor with IC50 of 770 nM, inhibits Nek2 via alkylation of residue Cys22, does not inhibit Cdk1/CycB (IC50>20 uM).
PC-20308

CCT241950

CCT241950 (CCT 241950) is a small molecule NEK2 inhibitor, induces Tyr70Nek2 to jut into the ADP-binding pocket.

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