| Cat. No. |
Product Name |
Information |
| PC-61482 |
TAI-95
|
TAI-95 (T-1101, TAI 95) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines). |
| PC-61480 |
INH154
|
INH154 is a novel small molecules disrupting Hec1/Nek2 interaction, inhibits HeLa and MDA-MB-468 cancer cells growth with IC50 of 0.20 and 0.12 uM, respectively. |
| PC-42194 |
INH-6
|
A small molecule inhibitor of Nek2/Hec1 that inhibits cell growth of MB231, MB468, HeLa and K562 cells with IC50 of 1.7, 2.1, 2.4 and 2.5 uM, respectively. |
| PC-20311 |
Nek2 inhibitor 66
|
Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM. |
| PC-20310 |
T-1101 tosylate
|
T-1101 tosylate (TAI-95 tosylate) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines). |
| PC-20309 |
JH295
|
JH295 (JH-295) is a potent, selective and irreversible Nek2 kinase inhibitor with IC50 of 770 nM, inhibits Nek2 via alkylation of residue Cys22, does not inhibit Cdk1/CycB (IC50>20 uM). |
| PC-20308 |
CCT241950
|
CCT241950 (CCT 241950) is a small molecule NEK2 inhibitor, induces Tyr70Nek2 to jut into the ADP-binding pocket. |
