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Cat. No. Product Name Information
PC-49207

TRULI

TRULI is a small molecule Yap signaling activator, acts as an ATP-competitive inhibitor of Lats kinases in vitro (Lats1 kinase, IC50=0.2 nM, 10 uM ATP), prevents Yap phosphorylation in the cell-based assays with EC50 of 510 nM.
PC-49206

TDI-011536

TDI-011536 is a potent, ATP-competitive inhibitor of Lats kinases with IC50 of 0.76 nM (2 mM ATP) in vitro assays, prevents Yap phosphorylation in the cell-based assays with EC50 of 10 nM.
PC-73093

GA-017

GA-017 (GA017) is a potent, selective, ATP-competitive LATS kinase (LATS1/2) inhibitor with IC50 of 4.10/3.92 nM, respectively, promotes cell growth.
PC-72700

SBP-3264

SBP-3264 (SBP3264) is a sepecific inhibitor of Hippo signaling pathway kinases STK3 and STK4 with low nanomolar potency.
PC-38143

TEAD-IN-2

TEAD-IN-2 (TEAD antagonist 2) is a small molecule TEAD antagonist (TEAD2 IC50=603 nM FP assays, SPR Kd=229 nM) that binds the TEAD lipid pocket and disrupts TEAD S-palmitoylation.
PC-38111

VT02484

VT02484 is the negative control compound of VT02956, which is a highly potent Hippo pathway kinase LATS inhibitor..
PC-38110

VT02956

VT02956 is a potent, specific inhibitor of Hippo pathway kinase LATS with IC50 of 0.76 nM (LATS1) and 0.52 nM (LATS2), respectively.

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