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Cat. No. Product Name Information
PC-49244

iJMJD6

iJMJD6 is a potent, specific small-molecule JMJD6 inhibitor that specifically binds to JMJD6 (ITC Kd=3.83 uM) and competes with α-KG and the substrate for binding, inhibits the demethylase activity of JMJD6 with IC50 of 149.6 nM.
PC-72385

FTO inhibitor CS1

FTO inhibitor CS1 (NSC 337766) is a potent, selective small-molecule inhibitor of m6A demethylase FTO, inhibits m6A demethylation with IC50 of 142.6 nM in vitro (cell-free) assays.
PC-72259

TACH101

TACH101 (QC8222, TACH 101) is a reversible, α-ketoglutarate competitive, selective and potent inhibitor of KDM4 isoforms A-D with IC50 values of 80 nM against all four isoforms.
PC-38256

ALKBH5 inhibitor 6

ALKBH5 inhibitor 6 is a small molecule inhibitor of RNA 6-N-methyladenosine (m6A) demethylase ALKBH5, inhibits ALKBH5 RNA m6A demethylation activity with IC50 of 1.79 uM.
PC-38255

ALKBH5 inhibitor 3

ALKBH5 inhibitor 3 is a small molecule inhibitor of RNA 6-N-methyladenosine (m6A) demethylase ALKBH5, inhibits ALKBH5 RNA m6A demethylation activity with IC50 of 0.84 uM.
PC-38254

MV1035

MV1035 (MV-1035) is a novel small molecule that reduce U87 GBM cells migration and invasiveness, targeting m6A demethylase ALKBH5, also inhibits ALKBH2.
PC-38127

INCB059872

INCB059872 (INCB-059872, INCB 59872) is a potent, selective, and orally active lysine-specific demethylase 1 (LSD1) inhibitor.

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