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Cat. No. Product Name Information
PC-38171

GSK8612

GSK8612 (GSK-8612) is a highly selective, potent TBK1 inhibitor, inhibits recombinant TBK1 with pIC50 of 6.8 in biochemical functional assays.
PC-35769

SR12343

SR12343 (SR-12343) is a novel NF-κB essential modulator (NEMO)-binding domain (NBD) mimetic for inhibiting IKK/NF-κB activation, inhibits TNF-α-mediated NF-κB activation with IC50 of 11.34 uM in luciferase assays.
PC-61282

AS602868

AS602868 (SPC 839) is a potent, selective and ATP-competitive inhibitor of IKK2 with IC50 of 60 nM and Ki of 20 nM, also interfers directly with FLT3 kinase activation.
PC-61066

SU-909

SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM).
PC-43044

WS-3

WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM.
PC-45916

Bay 65-1942

Bay 65-1942 (BAY651942) is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM.
PC-42418

IMD-0354

IMD-0354 (IMD0354) is a potent IκB kinase β (IKKbeta) inhibitor, also is a potent inhibitor of glutamine uptake.

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