| Cat. No. |
Product Name |
Information |
| PC-47055 |
ARTS mimetic A4
|
ARTS mimetic A4 is a small molecule that mimics the function of the pro-apoptotic ARTS (Sept4_i2) protein, binds the ARTS pocket in XIAP-BIR3, but not cIAP1, specifically promotes degradation of XIAP and induces caspase-mediated cell death. |
| PC-63391 |
ASTX660
|
Tolinapant (ASTX660) is a novel potent IAP antagonist that targets the BIR3 domain of cIAP1/2 and XIAP with IC50 of 12 nM and <40 nM. |
| PC-45289 |
Embelin
|
Embelin (Embelic acid, Emberine, NSC-91874) is a cell-permeable benzoquinone compound that exhibits antitumor properties. |
| PC-20236 |
RMT 5265
|
RMT 5265 (RMT5265) is a potent, small molecule bivalent mimic of Smac, inhibits XIAP and cIAP1/2 through the BIR3 domain. |
| PC-72363 |
SW IV-134
|
SW IV-134 is a sigma-2/SMAC drug conjugate, chemically linked the sigma-2 ligand SW43 to the Smac mimetic SW IV-52. |
| PC-72362 |
SW IV-52
|
SW IV-52 is a pro-apoptotic small molecule SMAC mimetic and XIAP-inhibitor. |
| PC-35081 |
MX107
|
MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM. |
