| Cat. No. |
Product Name |
Information |
| PC-21024 |
TIM-3 inhibitor 38
|
TIM-3 inhibitor 38 is a small-molecule inhibitor of T-cell immunoglobulin and mucin domain 3 (TIM-3; HAVCR2) with Ki of 70 nM in FPA competition assays. |
| PC-21023 |
TIM-3 inhibitor A-41
|
TIM-3 inhibitor A-41 is small-molecule inhibitor of T-cell immunoglobulin and mucin domain 3 (TIM-3; HAVCR2) with SPR Kd value of 0.61 uM. |
| PC-38590 |
VISTA inhibitor M351-056
|
VISTA inhibitor M351-056 is a small molecule compound having affinity with VISTA. |
| PC-38588 |
Compound 6809-0223
|
Compound 6809-0223 is a small-molecule antagonist targeting the immune checkpoint VISTA, shows good binding affinity for murine VISTA (Kd=647 nM, VISTA-ECD). |
| PC-38587 |
L557-0155
|
L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth. |
| PC-38146 |
VISTA inhibitor III
|
VISTA inhibitor III is a small-molecule ligand for immune checkpoint VISTA with IC50 of 480 nM in FRET assay. |
| PC-38145 |
NSC622608
|
NSC622608 (NSC 622608) is the first small-molecule ligand for immune checkpoint VISTA with IC50 of 4.8 uM in FRET assay. |
