| Cat. No. |
Product Name |
Information |
| PC-49285 |
BTB-1
|
BTB-1 (KIF18A inhibitor BTB-1) is a selective and ATP-competitive mitotic kinesin KIF18A inhibitor, BTB-1 potently inhibits the ATPase activity of Kif18A with IC50 of 1.69 uM, does not inhibit other mitotic kinesins. |
| PC-72904 |
AMG650
|
AMG650 (Sovilnesib) is an oral, first in class, selective small molecule inhibitor of KIF18A for treatment of advanced solid tumors. |
| PC-72726 |
Azo-EMD
|
Azo-EMD is a cell permeable, photoswitchable compound that inhibits mitotic kinesin Eg5 more potently in its light-induced cis form, used for optical control mitosis. |
| PC-63578 |
Kif15-IN-1
|
Kif15-IN-1 is a potent, selective inhibitor of KIF15 motility, can act synergistically with Eg5 inhibitors to impair cancer cell proliferation.. |
| PC-62405 |
MAC1
|
MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity. |
| PC-42308 |
Monastrol
|
Monastrol potent, specific, allosteric and reversible mitotic kinesin Eg5 inhibitor with IC50 of 14 uM (microtubule motility inhibition). |
| PC-45861 |
Ispinesib
|
Ispinesib (SB-715992) is a potent, selective, cell-permeable, allosteric inhibitor of Eg5 (mitotic kinesin KSP) with Ki of 2.3 nM. |
