| Cat. No. |
Product Name |
Information |
| PC-42938 |
MALT1 inhibitor MI-2
|
MALT1 inhibitor MI-2 is a selective, irreversible MALT1 paracaspase inhibitor with IC50 of 5.84 uM, displays little activity against the related caspase family members caspase-3, -8, and -9. |
| PC-20142 |
MALT1 inhibitor 37
|
MALT1 inhibitor 37 is a potent, selective and oral bioavailable MALT1 inhibitor with IC50 of 93 nM, shows high potency for inhibiting IL-2 production with IC50 of 1.4 uM. |
| PC-49483 |
MLT-943
|
MLT-943 is a potent and selective MALT1 protease inhibitor with IC50 of 40 nM in IL-2 reporter gene assay (Jurkat T cells), inhibits human PBMC IL-2 release with IC50 of 74 nM. |
| PC-49482 |
MLT-985
|
MLT-985 (MLT985) is a potent, highly selective allosteric MALT1 inhibitor with biochemical IC50 of 3 nM, and 20 nM in IL-2 reporter gene assay (Jurkat T cells). |
| PC-49481 |
MLT-827
|
MLT-827 is a potent and selective inhibitor of MALT1 paracaspase activity with IC50 of 5 nM. |
| PC-49480 |
MLT-231
|
MLT-231 (MLT231) is a highly potent, selective, allosteric MALT1 inhibitor with biochemical IC50 of 9 nM, inhibits MALT1 cleavage of the BCL10 substrate with IC50 of 0.16 uM. |
| PC-49479 |
MALT1 inhibitor 8
|
MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1. |
