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Cat. No. Product Name Information
PC-23370

NDI-101150

HPK1 inhibitor

NDI-101150 is a potent and highly selective hematopoietic progenitor kinase 1 (HPK1, MAP4K1) inhibitor with biochemicals IC50 of 0.7 nM and cellular IC50 of 41 nM.
PC-21340

DS21150768

HPK1/MAP4K1 inhibitor

DS21150768 is a potent selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with IC50 of 3.27 nM in cell-free HPK1 assays, binds to HPK1 with an affinity constant (KD) of 6.08 nM.
PC-20029

F389-0746

MAP4K4 inhibitor

F389-0746 is a potent, selective and orally active MAP4K4 inhibitor with IC50 of 120.7 nM.
PC-49661

BAY-405

HPK1/MAP4K1 inhibitor

BAY-405 (BAY405) is a potent, selective MAP4K1 (HPK1) inhibitor with IC50 of 6 nM in binding competition assays.
PC-38665

HPK inhibitor compound 1

HPK1 inhibitor

HPK inhibitor compound 1 is an allosteric, inactive conformation-selective HPK1 inhibitor, binds to unphosphorylated HPK1 and >24-fold more potently than active HPK1.
PC-72305

ZYF0033

HPK1/MAP4K1 inhibitor

ZYF0033 (ZYF 0033) is potent, selective, small-molecule inhibitor of HPK1 (MAP4K1) with IC50 of <10 nM based on the phosphorylation inhibition of MBP protein.
PC-72304

GNE-1858

HPK1/MAP4K1 inhibitor

GNE-1858 (GNE1858) is a potent, selective, ATP-competitive inhibitor of HPK1 (MAP4K1) with IC50 of 1.9 nM in the SLP76 phosphorylation assay.
PC-72303

A-745

HPK1/MAP4K1 inhibitor

A-745 (A745) is a selective and potent HPK1 chemical probe (inhibitor) of HPK1 (MAP4K1) with IC50 of 4 nM.
PC-72055

HPK1 inhibitor CompK

HPK1/MAP4K1 inhibitor

Compound K (HPK1 inhibitor CompK) is a novel, potent, highly selective HPK1 (MAP4K1) kinase inhibitor with IC50 of 2.6 nM, 50-fold selectivity against other members of the MAP4K family.
PC-72013

HPK1 inhibitor 1

HPK1/MAP4K1 inhibitor

HPK1 inhibitor 1 is a highly potent, selective inhibitor of HPK1/MAP4K1 with biochemical IC50 of 0.0465 nM.
PC-36139

DMX-5804

MAP4K4 inhibitor

DMX-5804 (DMX5804) is a potent, selective small-molecule inhibitor of MAP4K4 with IC50 of 3 nM.
PC-35005

MAP4K4-IN-37

MAP4K4 inhibitor

MAP4K4-IN-37 is a potent, selective, orally active inhibitor of serine-threonine kinase MAP4K4 with IC50 of 0.4 nM.

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