| Cat. No. |
Product Name |
Information |
| PC-20026 |
Darizmetinib
|
Darizmetinib (HRX-0215, HRX0215) is a potent, selective inhibitor of MKK4 (MAP2K4/SEK1), shows potential for promoting liver regeneration or reducing or preventing hepatocyte death. |
| PC-72995 |
URML-3881
|
URML-3881 (URML3881) is a potent, specific MEK1/2 inhibitor IC50 of 30 nM in a cell-free kinase inhibition assay. |
| PC-72697 |
MAP855
|
MAP855 (MAP-855) is a highly potent, selective, ATP-competitive MEK1/2 inhibitor (pERK IC50=5 nM) with equipotent inhibition of WT and mutant MEK1/2. |
| PC-72696 |
DTP3
|
DTP3 (MKK7 inhibitor DTP3) is a specific D-tripeptide that disrupts the GADD45β/MKK7 complex (Kd=64.8 nM), kills MM cells effectively, and lacks toxicity to normal cells. |
| PC-72695 |
MEK4 inhibitor 6ff
|
MEK4 inhibitor 6ff is potent, selective MEK4 inhibitor with IC50 of 66 nM. |
| PC-72692 |
MEK4 inhibitor 15o
|
MEK4 inhibitor 15o is potent, selective, cell permeable MEK4 inhibitor with IC50 of 83 nM. |
| PC-72689 |
MEK4 inhibitor 10e
|
MEK4 inhibitor 10e is potent, selective cell permeable MEK4 inhibitor with IC50 of 61 nM. |
