| Cat. No. |
Product Name |
Information |
| PC-49013 |
CH-3-8
|
CH-3-8 is a novel microtubule polymerization inhibitor with little susceptible to transporter-mediated chemoresistance, binds to the colchicine-binding site in tubulin protein, disrupts microtubule dynamics at the nanomolar concentration in MIA PaCa-2 and PANC-1 pancreatic cancer cell lines. |
| PC-49011 |
QW-296
|
QW-296 is a novel microtubule destabilizer with little susceptible to transporter-mediated drug resistance, disturbs the microtubule dynamics at the nanomolar concentration in A375 and B16F10 melanoma cells. |
| PC-47072 |
R-huezole
|
R-huezole is a phase-separating small molecule that forms liquid droplets to selectively sequester tubulin, enters cultured human cells and prevents cell mitosis by forming tubulin-concentrating condensates in cells. |
| PC-35597 |
VERU-111
|
VERU-111 (Sabizabulin, VERU111) is an oral cytoskeleton disruptor that targets and inhibits microtubules to disrupt androgen receptor transport into the nucleus, shows broad antiviral activity by disrupting the intracellular transport of viruses such as SARS CoV-2. |
| PC-43537 |
Eribulin mesylate
|
Eribulin mesylate (B1939, E7389, ER-086526) is a macrocyclic ketone analogue of halichondrir B, shows sub-nM growth inhibitory activities in vitro against numerous human cancer cell lines via inhibition of tubulin polymerization. |
| PC-43536 |
Eribulin
|
Eribulin (B1939, E7389, ER-086526) is a macrocyclic ketone analogue of halichondrir B, shows sub-nM growth inhibitory activities in vitro against numerous human cancer cell lines via inhibition of tubulin polymerization. |
| PC-42620 |
Lexibulin dihydrochloride
|
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
