| Cat. No. |
Product Name |
Information |
| PC-38356 |
Darovasertib
|
Darovasertib (LXS 196, IDE 196) is a selectve, oral small molecule protein kinase C (PKC) inhibitor, demonstrating promising efficacy in metastatic uveal melanoma (MUM) combined with Crizotinib. |
| PC-73059 |
NP627
|
NP627 (NP-627) is a specific small-molecule inhibitor of protein kinase C deltaI (PKCδI) with Kd of 1 nM. |
| PC-73053 |
PKCθ inhibitor 22
|
PKCθ inhibitor 22 is a potent, selective, orally bioavailable inhibitor of Protein Kinase Cθ (PKCθ) with IC50 of 6 nM. |
| PC-72784 |
CC-90005
|
CC-90005 (CC90005) is a potent, selective PKC-θ inhibitor with IC50 of 8 nM, >500-fold selectivity over PKC-γ. |
| PC-38022 |
TPPB
|
TPPB is a highly potent, selectiveand cell permeable protein kinase C (PKC) activator with Ki of 11.9 nM. |
| PC-36023 |
PZ09
|
PZ09 (PKC-zeta inhibitor 9, PKC-ζ inhibitor PZ9) is a potent, isoform selective PKC-zeta (PKC-ζ) inhibitor with IC50 of 5.18 nM, displays excellent selectivity (>200-fold) over other PKC isoforms with exception of PKC-i (10-fold). |
| PC-35337 |
ζ-Stat
|
ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, showed only 13%
inhibition on PKC-I at 20 uM. |
