| Cat. No. |
Product Name |
Information |
| PC-47062 |
TXS-8
|
TXS-8 is a specific, small molecule binder of Rpn-6 with KD of 14 uM, Rpn-6 is a subunit of the 19S regulatory particle (RP) of 26s proteasome. |
| PC-72402 |
M3258
|
M3258 (M 3258) is a potent, reversible, highly selective and orally acitve LMP7 inhibitor with cellular IC50 of 4.1 nM. |
| PC-35491 |
TCH-165
|
TCH-165 is a specific small molecule modulator of proteasome assembly, regulates the dynamic equilibrium between the 20S and 26S proteasome complexes, favoring 20S-mediated protein degradation. |
| PC-43439 |
MG-132
|
MG-132 (Z-Leu-leu-leu-al, Zlllal) is a potent, reversible, and cell-permeable proteasome inhibitor with IC50 of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively. |
| PC-61352 |
O-phenanthroline
|
A selective inhibitor of 26S proteasome subunit Rpn11 with IC50 of 10±2 uM. |
| PC-61193 |
CSN5i-3
|
CSN5i-3 (CSN5 inhibitor 3) is a potent, selective and orally available inhibitor of CSN5 with IC50 of 5.8 nM, the proteolytic subunit of COP9 signalosome (CSN). |
| PC-61132 |
Rpn11 inhibitor 35
|
Rpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM,100-fold selectivity over Csn5 and 10-fold selectivity over AMSH. |
