| Cat. No. |
Product Name |
Information |
| PC-72723 |
MRIA9
|
MRIA9 is a potent, selective dual SIK/PAK inhibitor, inhibits SIK1/2/3 with cellular IC50 of 586/180/127 nM, respectively. |
| PC-63122 |
YKL 06-061
|
YKL 06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 of 6.56/1.77/20.5 nM for SIK1/2/3, respectively. |
| PC-61766 |
ARN-3236
|
ARN-3236 (ARN3236) is a novel potent, selective, and orally active SIK2 inhibitor with IC50 of <1 nM. |
| PC-42327 |
YKL-05-099
|
YKL-05-099 (YKL 05-099) is a novel potent, selective pan-SIK inhibitor with IC50 of 10, 40 and 30 nM for SIK1, 2 and 3, respectively. |
| PC-20809 |
SIK inhibitor M22
|
SIK inhibitor M22 is a potent, selective pan-SIK (salt-inducible kinase) with IC50 of 72, 89 and 18 nM for SIK1, SIK2 and SIK3 in NanoBERT assays, respectively. |
| PC-20664 |
GLPG3970
|
GLPG3970 (GLPG 3970) is a potent, selective first-in-class salt inducible kinase SIK2/SIK3 inhibitor in development for inflammatory indications. |
| PC-49563 |
SK-124
|
SK-124 (SK124) is a potent, selective, orally active SIK2/SIK3 inhibitor with IC50 of 8.8/11.3 nM in cell-based NanoBRET assays, 15-fold selectivity versus SIK1. |
