| Cat. No. |
Product Name |
Information |
| PC-49248 |
JYQ-42
|
JYQ-42 is a potent, selective SIRT6 allosteric inhibitor, effectively inhibits SIRT6 deacetylation with IC50 of 2.33 uM, inhibits the deacetylation activity of SIRT6 in pancreatic cancer cell lines. |
| PC-49081 |
MC3138
|
MC3138 is a potent and selective small-molecule SIRT5 activator, inhibits proliferation in SIRT5-low PDAC cell lines and organoids. |
| PC-47061 |
SRT2104
|
SRT2104 (GSK2245840) is a highly selective small molecule activator of the NAD+ dependent deacetylase SIRT1. |
| PC-38543 |
AGK2
|
AGK2 is a cell-permeable, selective inhibitor of SIRT2 with IC50 of 3.2 uM, shows minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. |
| PC-72771 |
YC8-02
|
YC8-02 is a small molecule mitochondrial-targeting SIRT3 inhibitor with IC50 of 0.53 uM. |
| PC-72770 |
NH4-6
|
NH4-6 is a potent pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively. |
| PC-72768 |
NRD167
|
NRD167 is a potent and selective, cell-permeant SIRT5 inhibitor. |
