| Cat. No. |
Product Name |
Information |
| PC-73239 |
HS-276
|
HS-276 is a potent, highly selective and orally bioavailable TAK1 inhibitor with Ki of 2.5 nM. |
| PC-61199 |
PF-05381941
|
PF-05381941 (PF 05381941, PF05381941) is a potent, dual TAK1/p38a inhibitor with IC50 of 156/186 nM respectively, with good kinome selectivity against 50 representative kinases. |
| PC-61197 |
Takinib
|
Takinib is a potent, selective TAK1 inhibitor with IC50 of 9.5 nM, selectively induces apoptosis following TNF-a stimulation. |
| PC-62868 |
(5Z)-7-Oxozeaenol
|
(5Z)-7-Oxozeaenol is a potent and selective TAK1 inhibitor with IC50 of 8 nM, displays >33-fold and >62-fold selectivity over MEKK1 and MEKK4 respectively. |
| PC-62810 |
TAK1-IN-1
|
TAK1-IN-1 is a potent, selective, Type I (ATP-competitive, DFG-in) TAK1 inhibitor with Kd of 59 nM, a thienopyrimidine scaffold that serves as a good starting point for medicinal chemistry.. |
| PC-61198 |
5Z-7-Oxozeaenol
|
A potent, selective TAK1 inhibitor with IC50 of 8 nM, displays >33-fold and >62-fold selectivity over MEKK1 and MEKK4 respectively. |
| PC-70029 |
Minnelide
|
A water-soluble prodrug of triptolide that is highly effective in reducing pancreatic tumor growth and spread, and improving survival. |
