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Cat. No. Product Name Information
PC-49109

SY-LB-35

SY-LB-35 is a highly effective small molecule full agonist of bone morphogenetic protein (BMP) receptor signaling, significantly increases the cell number and cell viability in the C2C12 myoblast cell line.
PC-72619

PF-06952229

PF-06952229 (MDV6058) is a potent, selective and orally active TGFBR1 (ALK5) inhibitor with IC50 of 24 nM.
PC-35519

BLU-782

Fidrisertib (BLU-782) is a potent, selective inhibitor of ALK2 (ACVR1) mutant R206H with IC50 of <10 nM.
PC-63322

JL5

JL5 is a novel potent, selective BMP receptor inhibitor with IC50 of 1, <5 and 2 nM for ALK2/ACVR1, ALK3/BMPR1A and ALK6/BMPR1B, respectively.
PC-63129

LY 3200882

LY 3200882 (LY3200882) is a novel potent, highly selective, ATP competitive TGF-β receptor type 1 (TGFβRI, ALK5) inhibitor.
PC-61454

TP-0427736

TP-0427736 (TP0427736) is a novel potent and selective ALK5 inhibitor with IC50 of 2.72 nM, displays 300-fold selecitvity over ALK3.
PC-60916

San78-130

San78-130 is a potent, selective activin receptor-like Kinase 1 (ALK1) inhibitor with IC50 of 62 nM, with greater selectivity compared with L-783277.

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