| Cat. No. |
Product Name |
Information |
| PC-49109 |
SY-LB-35
|
SY-LB-35 is a highly effective small molecule full agonist of bone morphogenetic protein (BMP) receptor signaling, significantly increases the cell number and cell viability in the C2C12 myoblast cell line. |
| PC-72619 |
PF-06952229
|
PF-06952229 (MDV6058) is a potent, selective and orally active TGFBR1 (ALK5) inhibitor with IC50 of 24 nM. |
| PC-35519 |
BLU-782
|
Fidrisertib (BLU-782) is a potent, selective inhibitor of ALK2 (ACVR1) mutant R206H with IC50 of <10 nM. |
| PC-63322 |
JL5
|
JL5 is a novel potent, selective BMP receptor inhibitor with IC50 of 1, <5 and 2 nM for ALK2/ACVR1, ALK3/BMPR1A and ALK6/BMPR1B, respectively. |
| PC-63129 |
LY 3200882
|
LY 3200882 (LY3200882) is a novel potent, highly selective, ATP competitive TGF-β receptor type 1 (TGFβRI, ALK5) inhibitor. |
| PC-61454 |
TP-0427736
|
TP-0427736 (TP0427736) is a novel potent and selective ALK5 inhibitor with IC50 of 2.72 nM, displays 300-fold selecitvity over ALK3. |
| PC-60916 |
San78-130
|
San78-130 is a potent, selective activin receptor-like Kinase 1 (ALK1) inhibitor with IC50 of 62 nM, with greater selectivity compared with L-783277. |
