| Cat. No. |
Product Name |
Information |
| PC-35708 |
ULK-100
|
ULK-100 (ULK100) is a potent and selective ULK1 inhibitor with in vitro IC50 of 1.6 nM, inhibits ULK2 with IC50 of 2.6 nM. |
| PC-35707 |
ULK-101
|
ULK-101 (ULK101) is a potent and selective ULK1 inhibitor with in vitro IC50 of 8.3 nM, inhibits ULK2 with IC50 of 30 nM. |
| PC-63368 |
BL-918
|
BL-918 is a small molecule activator of ULK1 with EC50 of 24 nM (243% kinase activity at 100 nM), induces autophagy via the ULK complex in SH-SY5Y cells. |
| PC-43328 |
MRT67307
|
MRT67307 is a potent, dual inhibitor of IKKε and TBK-1 with IC50 of 160 and 19 nM at 0.1 mM ATP in vitro, also potently inhibit ULK1 and ULK2 in vitro (IC50=45 and 38 nM) and block autophagy in cells. |
| PC-63085 |
LYN-1604
|
LYN-1604 is a potential ULK1 agonist (enzymatic activity=195.7% at 100 nM and IC50=1.66 uM against MDA-MB-231 cells), displays a good effect on ULK1 activation with an EC50 of 18.94 nM. |
| PC-60144 |
SR-20295
|
SR-20295 (SR20295) is a novel potent ULK1 inhibitor with IC50 of 45 nM. |
| PC-42021 |
MRT-68921 hydrochloride
|
MRT-68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively. |
