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Cat. No. Product Name Information
PC-38176

NV-5138

NV-5138 (NV5138) is the first selective, orally bioavailable brain mTORC1 activator, binds to Sestrin2 (Kd=1.5 uM) and activates mTORC1 both in vitro and in vivo.
PC-36112

MTI-31

MTI-31 (LXI-15029, mTOR inhibitor-31) is a novel potent, selective mTORC1/mTORC2 inhibitor with Kd of 0.2 nM (mTOR), displays >5,000-fold selectivity over PIK3CA, PIK3CB and PIK3G.
PC-35517

ICSN3250

ICSN3250 (ICSN-3250) is a halitulin-analogue that acts as a new-class, specific mTOR inhibitor through a mechanism distinct from previous mTOR inhibitors.
PC-43497

Sapanisertib

Sapanisertib (INK-128, MLN0128) is a potent, ATP-competitive, orally active dual mTORC1/2 inhibitor with Ki of 1.4 nM in cell-free assays, >200-fold selectivity over calss I PI3K isoforms.
PC-60555

NV-128

NV-128 (LY-303511) is a novel isoflavone derivative that inhibits mTOR and promotes caspase-independent cell death.
PC-60554

ME-344

ME-344 is a novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM.
PC-60418

RapaLink-1

RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors.

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