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(±)-U-50488 hydrochloride

Chemical Structure : (±)-U-50488 hydrochloride

CAS No.: 67197-96-0

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(±)-U-50488 hydrochloride ((±)-trans-(1R,2R)-U-50488 hydrochloride)

Catalog No.: PC-60716Not For Human Use, Lab Use Only.

(±)-U-50488 hydrochloride is a potent, selective kappa-opioid receptor agonist with no μ-opioid antagonist effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    (±)-U-50488 hydrochloride is a potent, selective kappa-opioid receptor agonist with no μ-opioid antagonist effects.
    (±)-U-50488 hydrochloride shows analgesic, diuretic and antitussive effects, and reverses the memory impairment produced by anticholinergic drugs in vivo.

    Physicochemical Properties

    M.Wt 405.79
    Formula C19H26Cl2N2O.HCl
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    25 mM in H2O
    Chemical Name/SMILES

    trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride

    References

    1. Tao PL, et al. Eur J Pharmacol. 1994 May 2;256(3):281-6.

    2. Suarez-Roca H, et al. J Pharmacol Exp Ther. 1993 Feb;264(2):648-53.

    3. Su MT, et al. Br J Pharmacol. 1998 Feb;123(4):625-30.

    4. Vonvoigtlander PF, et al. J Pharmacol Exp Ther. 1983 Jan;224(1):7-12.

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