| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38626 |
IKAM-1
|
2345648-37-3 |
IKAM-1 (Compound 39-100) is an orally bioavailable, small-molecule IKKβ activation modulator (IKAM) that selectively targets MAP3K1, inhibits TNF-α-induced IKKβ-mediated NF-κB activation in A549 cells with IC50 of 4.7 uM. |
| PC-35427 |
GS-444217
|
1262041-49-5 |
GS-444217 (GS444217) is a potent, selective, ATP-competitive, orally available inhibitor of ASK1 with Kd/IC50 of 4.1/2.87 nM. |
| PC-62728 |
SW-083688
|
422281-45-6 |
SW-083688 (SW083688) is a potent, highly selective TAOK2 (Thousand-And-One Kinase 2, MAP3K17) inhibitor with IC50 of 1.3 uM. |
| PC-60150 |
ASK1-IN-19
|
2089638-10-6 |
AKS1-IN-19 is a novel potent, selective and orally active ASK1 (MAP3K5) inhibitor with pIC50 of 8.3. |
| PC-60092 |
GNE-8505
|
1620574-24-4 |
GNE-8505 (GNE8505) is a potent, selective and CNS-penetrant inhibitor of dual leucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. |
| PC-45794 |
Tpl2-IN-34
|
915363-56-3 |
A potent, selective Tpl2 (cot/MAP3K8) inhibitor with IC50 of 1.6 nM. |
| PC-45565 |
Selonsertib
|
1448428-04-3 |
Selonsertib (GS-4997) is a highly selective and potent, ATP-competetive inhibitor of ASK1 (Apoptosis Signal-regulating Kinase 1, MAP3K5) with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. |
