| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-61390 |
Nidufexor
|
1773489-72-7 |
Nidufexor (LMB763, LMB-763) is a novel potent farnesoid X receptor (FXR) agonist for the treatment of non-alcoholic steatohepatitis (NASH) and hepatobiliary disorders. |
| PC-61368 |
Cilofexor
|
1418274-28-8 |
Cilofexor (GS-9674, GS9674, PX-104) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models. |
| PC-60080 |
GSK-2324
|
1020567-30-9 |
GSK-2324 (GSK2324) is a potent, selective, full FXR agonist with EC50 of 120 nM in FRET assay. |
| PC-60079 |
LY-2562175
|
1103500-20-4 |
LY-2562175 (LY2562175, LY 2562175) is a novel potent, selective, partial FXR agonist with EC50 of 193 nM. |
| PC-60056 |
Tropifexor
|
1383816-29-2 |
Tropifexor (LJN-452, LJN452) is a novel highly potent, selective, orally acitive FXR full agonist with EC50 of 0.26 nM. |
| PC-42924 |
INT-747
|
459789-99-2 |
INT-747(Obeticholic acid, 6-ECDCA, 6-Ethylchenodeoxycholic acid) is a potent and selective FXR agonist (EC50=99 nM). |
| PC-47028 |
BMS-986339
|
2477873-64-4 |
BMS-986339 is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 34 nM (hFXR-Gal4), demonstrates differential induction of Fgf15 in the liver and ileum by FXR agonists in vivo. |
