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Cat. No. Product Name CAS No. Information
PC-73322

EZM0414

2411748-50-8 EZM 0414 is a potent, selective and orally bioavailable inhibitor of histone methyltransferase SETD2 with biochemical IC50 of 18 nM, >10,000-fold selectivity over other HMTases.
PC-72793

SNDX5613

2169919-21-3 Revumenib (SNDX-5613) is a potent and selective inhibitor of menin-MLL binding with Ki of 0.149 nM.
PC-72620

PF-06821497

1844849-10-0 PF-06821497 (PF 06821497) is a potent, selective, orally bioavailable Enhancer of Zeste Homolog 2 (EZH2) inhibitor with Ki of <1 nM against Y641N mutant.
PC-72444

JNJ-64619178

2086772-26-9 JNJ-64619178 (Onametostat, JNJ 64619178) is a selective, and potent PRMT5 inhibitor with Kiapp of 0.77 nM, inhibits the PRMT5/MEP50 complex impairing cancer cell proliferation.
PC-72299

NSD1 inhibitor BT5

2351225-46-0 NSD1 inhibitor BT5 is a covalent, small molecule inhibitor of NSD1 histone methyltransferase with IC50 of 1.4 uM, shows no covalent binding to NSD2.
PC-38300

MS1943

2225938-17-8 MS1943 (MS-1943) is a first-in-class, orally bioavailable EZH2 selective degrader that effectively reduces EZH2 levels in cells, inhibits EZH2 methyltransferase activity with IC50 of 120 nM.
PC-38151

SHIN1

2146095-85-2 SHIN1 (RZ-2994, RZ 2994) is a folate-competitive, cell-permeable inhibitor of human SHMT1/2 with biochemical IC50 of 5/13 nM.

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