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Cat. No. Product Name Information
PC-21395

NBI-961

NEK2 inhibitor

NBI-961 is a highly potent, selective inhibitor of NIMA related Kinase 2 (NEK2) and FLT3 with IC50 of 32 nM and 37 nM, respectively.
PC-20311

Nek2 inhibitor 66

Nek2 inhibitor

Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM.
PC-20310

T-1101 tosylate

Hec1-Nek2 inhibitor

T-1101 tosylate (TAI-95 tosylate) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
PC-20309

JH295

Nek2 inhibitor

JH295 (JH-295) is a potent, selective and irreversible Nek2 kinase inhibitor with IC50 of 770 nM, inhibits Nek2 via alkylation of residue Cys22, does not inhibit Cdk1/CycB (IC50>20 uM).
PC-20308

CCT241950

Nek2 inhibitor

CCT241950 (CCT 241950) is a small molecule NEK2 inhibitor, induces Tyr70Nek2 to jut into the ADP-binding pocket.
PC-61484

HCI-2389

Nek2 inhibitor

HCI-2389 is a potent, specific, irreversible NIMA-related Kinase 2 (NEK2) inhibitor with IC50 of 16.65 nM.
PC-61483

Nek2 inhibitor (R)-21

Nek2 inhibitor

A potent and selective NIMA-related Kinase 2 (NEK2) inhibitor with IC50 of 22 nM, >200-fold selectivity over Plk1, Mps1, Aurora A and CDK2.
PC-61482

TAI-95

Hec1-Nek2 inhibitor

TAI-95 (T-1101, TAI 95) is a potent, orally abioavailable Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=14.29-73.65 nM, breast cancer cell lines).
PC-61481

TAI-1

Hec1-Nek2 inhibitor

TAI-1 is a potent, small molecule Hec1 inhibitor that disrupts Hec1-Nek2 protein interaction wide anti-cancer spectrum (GI50=13.48 nM K562 cells).
PC-61480

INH154

Hec1/Nek2 inhibitor

INH154 is a novel small molecules disrupting Hec1/Nek2 interaction, inhibits HeLa and MDA-MB-468 cancer cells growth with IC50 of 0.20 and 0.12 uM, respectively.
PC-61479

Nek2 inhibitor 72

Nek2 inhibitor

Nek2 inhibitor 72 is a potent, ATP-competitive and relative selective Nek2 inhibitor with IC50 of 0.27 uM.
PC-61478

Nek2 inhibitor 3a

Nek2 inhibitor

Nek2 inhibitor 3a is a potent, relatively selective Nek2 inhibitor with IC50 of 82.74 nM in cell-free assays.

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