You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-Hec1/Nek2-Nek2 inhibitor 66
Nek2 inhibitor 66

Chemical Structure : Nek2 inhibitor 66

CAS No.: 1507367-00-1

Nek2 inhibitor 66 (NCL-00017509)

Catalog No.: PC-20311Not For Human Use, Lab Use Only.

Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM.

Packing Price Stock Quantity
100 mg Get quote
200 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Nek2 inhibitor 66 (NCL-00017509) is a potent, selective and irreversible inhibitor of Nek2 with IC50 of 62 nM, exhibits growth inhibitory activity in the SKBR3 cell line with GI50 of 2.2 uM.
Nek2 inhibitor 66 (5-10 uM) reduced C-Nap1 phosphorylation in U2OS cells.

Physicochemical Properties

M.Wt 292.30
Formula C15H12N6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-((6-ethynyl-9H-purin-2-yl)amino)phenyl)acetamide

References

1. Christopher J Matheson, et al. RSC Med Chem. 2020 May 22;11(6):707-731.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: