You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Bromodomain

Request The Product List ofBromodomain Bromodomain

Cat. No. Product Name CAS No. Information
PC-49210

GNE-064

1997321-20-6 GNE-064 (GNE064) is a potent, selective, and orally bioavailable inhibitor of the bromodomains of SMARCA2 (BRM), SMARCA4 (BRG1) and PBRM1 (polybromo-1) bromodomain 5 (PBRM1(5)) with IC50 of 10 nM, 16 nM and 18 nM, respectively.
PC-73385

SRX3305

2409965-28-0 SRX3305 is a potent, triple BTK/PI3K/BRD4 inhibitor with IC50 of 6.5 nM, 15 nM, and 4 nM toward BTK, PI3Kɑ and PI3Kδ respectively, inhibits BRD4 BD1 and BD2 with IC50 of 77 and 95 nM.
PC-72321

BRD8 inhibitor DN02

BRD8 inhibitor DN02 is a first-in-class selective and cellularly active probe for NuA4 factor BRD8 (BD1) with AlphaScreen IC50 of 48 nM, and Kd of 34 nM, displays IC50 of 0.64 uM in-cell engagement within BRET displacement assays, shows no affinity for BRD8 (BD2), CBP, and p300 (IC50>10 uM).
PC-38148

Alobresib

1637771-14-2 GS-5829 (GS5829, Alobresib) is a novel potent, selective BET inhibitor.
PC-38071

GSK778

2451862-42-1 GSK778 is a potent and selective inhibitor of bromodomain (BRD) BD1 with IC50 of 75 nM (BRD2-BD1), 41 nM (BRD3-BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively.
PC-38064

ODM-207

1801503-93-4 ODM-207 (ODM207) is a highly potent, selective and orally active pan-BET inhibitor with potent and broad antiproliferative effects.
PC-35848

TP-238

2415263-04-4 TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30 nM against CECR2 and 350 nM against BPTF in an alphascreen assay, KD of 10 nM for CECR2 and 120nM for BPTF in ITC assays.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com