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Cat. No. Product Name CAS No. Information


1997321-20-6 GNE-064 (GNE064) is a potent, selective, and orally bioavailable inhibitor of the bromodomains of SMARCA2 (BRM), SMARCA4 (BRG1) and PBRM1 (polybromo-1) bromodomain 5 (PBRM1(5)) with IC50 of 10 nM, 16 nM and 18 nM, respectively.


2409965-28-0 SRX3305 is a potent, triple BTK/PI3K/BRD4 inhibitor with IC50 of 6.5 nM, 15 nM, and 4 nM toward BTK, PI3Kɑ and PI3Kδ respectively, inhibits BRD4 BD1 and BD2 with IC50 of 77 and 95 nM.

BRD8 inhibitor DN02

BRD8 inhibitor DN02 is a first-in-class selective and cellularly active probe for NuA4 factor BRD8 (BD1) with AlphaScreen IC50 of 48 nM, and Kd of 34 nM, displays IC50 of 0.64 uM in-cell engagement within BRET displacement assays, shows no affinity for BRD8 (BD2), CBP, and p300 (IC50>10 uM).


1637771-14-2 GS-5829 (GS5829, Alobresib) is a novel potent, selective BET inhibitor.


2451862-42-1 GSK778 is a potent and selective inhibitor of bromodomain (BRD) BD1 with IC50 of 75 nM (BRD2-BD1), 41 nM (BRD3-BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively.


1801503-93-4 ODM-207 (ODM207) is a highly potent, selective and orally active pan-BET inhibitor with potent and broad antiproliferative effects.


2415263-04-4 TP-238 (TP238) is a CECR2/BPTF bromodomains chemical probe with IC50 of 30 nM against CECR2 and 350 nM against BPTF in an alphascreen assay, KD of 10 nM for CECR2 and 120nM for BPTF in ITC assays.

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