| Cat. No. |
Product Name |
Information |
| PC-62288 |
CeMMEC2
BRD4 inhibitor
|
CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1. |
| PC-62287 |
BAY299
BRPF1/TAF1 inhibitor
|
BAY 299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 and the second bromodomain of TAF1 with IC50 of 6 nM and 13 nM, respectively. |
| PC-62286 |
NI-57
BRPF bromodomain inhibitor
|
NI-57 is a potent inhibitor of the bromodomain of the BRPFs and binds to BRPF1B, BRPF2 and BRPF3 and with KD of 31 nM,108 nM and 408 nM (ITC), respectively. |
| PC-62285 |
BRPF1B TRIM24-IN-34
BRPF1B/TRIM24 inhibitor
|
BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively. |
| PC-62284 |
FT-1101
BET inhibitor
|
FT-1101 is a potent pan-BET bromodomain inhibitor that displays equipotent inhibition for BRD2, BRD3, BRD4, and BRDT with Kd < 20 nM. |
| PC-62283 |
BAY1238097
BET inhibitor
|
BAY 1238097 is a novel BET bromodomain inhibitor with IC50 of 50 nM, inhibits the interaction between BRD4, BRD3 or BRD2 and H4 with IC50 values of 63 nM, 609 nM and 2430 nM in the NanoBRET assay. |
| PC-62282 |
CPI 0610
|
Pelabresib (CPI 0610) is a potent, selective, and cell-active BET bromodomain inhibitor with IC50 of 39 nM for BRD4-BD1 in TR-FRET assay. |
| PC-62281 |
INCB054329
BET inhibitor
|
INCB 054329 (INCB054329) is a potent, selective, pan-BET bromodomain inhibitor with biochemical IC50 of 1-119 nM against BRD2, BRD3, and BRD4 and BRDT. |
| PC-62279 |
PFI-3
BRG/PB1 inhibitor
|
PFI-3 (PF-06687252) is a potent and cell active BRG/PB1 bromodomains inhibitor with Kd of 54-97 nM. |
| PC-62278 |
BRD-IN-17
Family VIII bromodomain inhibitor
|
BRD-IN-17 is a cell permeable, family VIII bromodomain tool compound with additional PB1(2) activity over and above that of PFI-3. |
| PC-62277 |
BRD-IN-26
PB1(5) inhibitor
|
BRD-IN-26 is a potent bromodomain inhibitor that binds the fifth bromodomain of PB1 (PB1(5)) with a KD of 124 nM, SMARCA2B and SMARCA4 with KD values of 262 and 417 nM, respectively. |
| PC-62276 |
OF-1
|
OF-1 is a potent bromodomain inhibitor that inhibits BRPF1B/2/3 bromodomains with Kd of 0.1/0.5/2.4 uM. |
