| Cat. No. |
Product Name |
Information |
| PC-42109 |
BI-7273
BRD9 inhibitor
|
BI-7273 is a potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay. |
| PC-45780 |
PF-CBP1 hydrochloride
CBP/p300 inhibitor
|
PF-CBP1 hydrochloride is a potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively. |
| PC-42090 |
GSK6853
BRPF1 inhibitor
|
GSK6853 (GSK-6853) is a potent, highly selective and cell-active BRPF1 bromodomain inhibitor with TR-FRET pIC50 of 8.1. |
| PC-42168 |
CPI-637
CBP/p300 inhibitor
|
CPI-637 is a potent and selective, cell-active CBP/EP300 bromodomain inhibitor with CBP BRET EC50 of 0.03 uM. |
| PC-43808 |
I-BET726
BET inhibitor
|
I-BET726 (GSK1324726A) is a potent and selective inhibitor of BET bromodomain with IC50 of 41 nM/31 nM/22 nM for BRD2/BRD3/BRD4 respectively. |
| PC-42230 |
TPOP146
CBP/p300 inhibitor
|
TPOP146 is a potent and selective CBP/p300 bromodomain inhibitor with Kd of 134 nM for CBP bromodomain, displays excellent selectivity over other bromodomains (>30-fold over BRD4 (1)). |
| PC-42029 |
Mivebresib
BET inhibitor
|
Mivebresib (ABBV-075) is a potent and orally available BET bromodomain inhibitor with Ki of 1.0, 12.2, 1.5, and 2.2 nM for BRD2, BRD3, BRD4 and BRDT, respectively. |
| PC-26563 |
BRD4 degrader ZZ2
BRD4 BD1 degrader
|
BRD4 degrader ZZ2 is CTLH-dependent BRD4 BD1 molecular glue degrader with DC50 of 169 nM in Jurkat cells, bridges YPEL5 and BRD4 BD1. |
| PC-26562 |
BRD4 degrader ZZ1
BRD4 BD1 degrader
|
BRD4 degrader ZZ1 is CTLH-dependent BRD4 BD1 molecular glue degrader with DC50 of 502 nM in Jurkat cells, bridges YPEL5 and BRD4 BD1. |
| PC-26535 |
16D10
TSLP production inhibitor, BRD4 ligand
|
16D10 is a small molecule inhibitor of TSLP production, binds to the BD1 domain of BRD4 with Kd of 1.5 uM, inhibits TSLP production by preventing BRD4 from binding to the TSLP promoter region. |
| PC-26533 |
TK-285
TSLP production inhibitor, BRD4 ligand
|
TK-285 is a potent inhibitor of TSLP production, binds to the BD1 domain of BRD4 with Kd of 190 nM, inhibits TSLP production by preventing BRD4 from binding to the TSLP promoter region. |
| PC-26515 |
MDP5
BRD4/PI3K inhibitor
|
MDP5 is a potent BRD4 and PI3K dual inhibitor, exhibits strong binding to BD1 and BD2. |
