| Cat. No. |
Product Name |
Information |
| PC-22287 |
CDD-1302
BRDT BD2 inhibitor
|
CDD-1302 (CDD1302) is a potent, selective second bromodomain (BD2) of BRDT and BRD4 inhibitor with IC50 of 8 and 12 nM, >1,000-fold and 300-fold selectivity over BRDT-BD1 and BRD4-BD1. |
| PC-22217 |
Rac EBET-590
BET inhibitor
|
Rac EBET-590 (EBET-590 Racemate) is a small molecule BET inhibitor. |
| PC-22216 |
EBET-590
BET inhibitor
|
EBET-590 (ER-001251206-000) is a small molecule BET inhibitor. |
| PC-22204 |
SDU-071
BRD4-p53 inhibitor
|
SDU-071 is a potent small molecule BRD4-p53 PPI inhibitor with IC50 of 2.7 uM, reduces the expression of BRD4-regulated genes, such as c-Myc and Mucin 5AC, and induces cell cycle arrest and apoptosis. |
| PC-22158 |
BBC0403
BRD2 inhibitor
|
BBC0403 (BBC-0403) is a specific BRD2 inhibitor with binding Kd of 41.4 uM and 7.6 uM for BRD2 (BD1) and BRD2 (BD2), inhibits the NF-κB and MAPK signalling pathways and the progression of osteoarthritis pathogenesis. |
| PC-21995 |
ZM145
pBRD4 inhibitor
|
ZM145 (pNPS145) is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 2.5 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication. |
| PC-21994 |
pNPS90
pBRD4 inhibitor
|
pNPS90 is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 1.5 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication. |
| PC-21993 |
pNPS14
pBRD4 inhibitor
|
pNPS14 is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 3.39 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication. |
| PC-21985 |
CBP bromodomain inhibitor 29
CBP bromodomain inhibitor
|
CBP-IN-29 is a potent, selective CBP bromodomain inhibitor with IC50 of 2.2 nM, displays exquisite selectivity over BRD4(1) (IC50=23 uM) and the broader bromodomain family. |
| PC-21984 |
CBP bromodomain inhibitor 27
CBP bromodomain inhibitor
|
CBP-IN-27 is a potent, selective CBP bromodomain inhibitor with IC50 of 3.6 nM, displays exquisite selectivity over BRD4(1) (IC50=11 uM) and the broader bromodomain family. |
| PC-21929 |
IACS-9571 hydrochloride
TRIM24 inhibitor
|
IACS-9571 hydrochloride is a potent, selective dual TRIM24-BRPF1 bromodomain inhibitor with Kd of 31 and 14 nM, respectively. |
| PC-21739 |
ZL0590
BRD4 BD1 inhibitor
|
ZL0590 is a potent, orally active, BRD4 BD1-selective inhibitor with IC50 of 90 nM for human BRD4 BD1. |
