| Cat. No. |
Product Name |
Information |
| PC-49385 |
KI-301690
DDR1 inhibitor
|
KI-301690 (KI 301690) is a novel potent, specific DDR1 inhibitor, synergized with gemcitabine to suppress the growth of pancreatic cancer cells. |
| PC-72924 |
VU6015929
DDR1/2 inhibitor
|
VU6015929 (VU 6015929) is a potent, selective, dual DDR1/2 inhibitor with IC50 of 4.67 nM and 7.39 nM for DDR1 and DDR2, respectively. |
| PC-38217 |
SR-302
Dual DDR/p38 inhibitor
|
SR-302 (SR302) is a potent, selective cell-active dual DDR/p38 inhibitor with IC50 of 23/18/125/196 nM for DDR1/DDR2/p38α/p38β, respectively. |
| PC-35847 |
DDR-TRK-1
DDR1 inhibitor
|
DDR-TRK-1 (DDR1 inhibitor 6j) is a potent, selective selective DDR1 inhibitor with IC50 of 9.4 nM, also potently inhibits TRK family with IC50 of 18-100 nM. |
| PC-35802 |
DDR1 inhibitor 2.45
DDR1 inhibitor
|
DDR1 inhibitor 2.45 (Compound 2.45) is a novel potent, selective, bioavailable Discoidin Domain Receptor 1 (DDR1) inhibitor with IC50 of 29 nM, displays 64-fold selectivity over DDR2 in biochemical assays. |
| PC-35543 |
Dual DDR1 and DDR2 inhibitor 5n
DDR1/2 inhibitor
|
Dual DDR1 and DDR2 inhibitor 5n is a highly potent, selective, dual Discoidin domain receptor DDR1 and DDR2 inhibitor with Kd of 7.9 and 8.0 nM, IC50 of 9.4 and 20.4 nM, repectively. |
| PC-35521 |
WRG-28
DDR2 inhibitor
|
WRG-28 (DDR2 inhibitor WRG-28) is a potent, selective, allosteric inhibitor of discoidin domain receptor 2 (DDR2) with binding IC50 of 230 nM. |
| PC-35349 |
DDR inhibitor X
DDR1/2 inhibitor
|
DDR inhibitor X is a potent discoidin domain receptor (DDR) inhibitor with IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM. |
| PC-63519 |
LCB 03-0110
DDR/Src inhibitor
|
LCB 03-0110 is a potent, ATP-competitive inhibitor of Discoidin domain receptor (DDR) family and c-Src tyrosine kinase family, as well as Btk and Syk. |
| PC-63518 |
DDR1 inhibitor 7rh
DDR1 inhibitor
|
DDR1 inhibitor 7rh is a potent, selective, ATP-competitive, orally available Discoidin domain receptor 1 (DDR1) inhibitor with IC50 of 6.8 nM in cell-free kinase assays. |
| PC-62396 |
ALW-II-49-7
DDR2 inhibitor
|
ALW-II-49-7 (DDR2-IN-1) is a potent, selective DDR2 inhibitor with IC50 of 18.6 nM, also shows ability to inhibit DDR1 and Ephrin-family kinases (IC50=40 nM for EphB2). |
| PC-62395 |
DDR2-IN-5
DDR2/Src inhibitor
|
DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM. |
