Discoidin Domain Receptor (DDR) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofDiscoidin Domain Receptor (DDR) Discoidin Domain Receptor (DDR)

Cat. No.	Product Name	Information
PC-62395	DDR2-IN-5 DDR2/Src inhibitor	DDR2-IN-5 is a potent, dual DDR2/SRC inhibitor with IC50 of 56/12 nM, potently suppresses DDR2 mutated cell lines HCC-366 and NCI-H2286 with IC50 of 0.44 uM and 0.29 uM.
PC-26074	TPKI-39 DDR1/2 inhibitor	TPKI-39 is a potent and selective chemical probe inhibitor for DDR1, DDR2 and FLT1 with IC50 of 380 nM, 120 nM and 65 nM respectively.
PC-26047	DDR2-IN-1 DDR2 inhibitor	DDR2-IN-1 is potent, selective DDR2 inhibitor with IC50 of 26 nM.
PC-24448	DDR1-IN-2 DDR1 inhibitor	DDR1-IN-2 is a potent and selective inhibitor of DDR1 receptor tyrosine kinase with IC50 of 47.6 nM, 4-fold selective over DDR-2 (IC50=145 nM), inhibits DDR1 autophosphorylation in cells.
PC-24447	DDR1-IN-1 DDR1 inhibitor	DDR1-IN-1 is a potent and selective inhibitor of DDR1 receptor tyrosine kinase with IC50 of 105 nM, 4-fold selective over DDR-2 (IC50=413 nM), inhibits DDR1 autophosphorylation in cells.
PC-23135	CH6824025 DDR1 inhibitor	CH6824025 is a potent, selective discoidin domain receptor 1 (DDR1) inhibitor, dose-dependently inhibits the phosphorylation of DDR1 induced by adding Type 1 collagen to U2OS cells stably expressing DDR1 with IC50 of 8.9 nM.
PC-63520	LCB 03-0110 dihydrochloride	LCB 03-0110 is a potent, ATP-competitive inhibitor of Discoidin domain receptor (DDR) family and c-Src tyrosine kinase family, as well as Btk and Syk.

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