| Cat. No. |
Product Name |
Information |
| PC-38883 |
Goflikicept
Anti-IL-1B fusion protein
|
Goflikicept (RPH-104) is a heterodimeric fusion protein containing IL-1R1 and IL-1RAcP linked to immunoglobulin heavy chains and is highly selectively binds IL-1B, affecting IL-1B signalling pathways, inhibits widespread inflammation. |
| PC-38865 |
Trebananib
Ang1 and Ang2 peptibody
|
Trebananib (AMG 386) is a first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2. |
| PC-38856 |
Batiraxcept
AXL Fc fusion
|
Batiraxcept (AVB‐S6‐500, AVB-500) is a first-in-class Fc fusion protein of the extracellular domain of AXL that binds the GAS6 ligand thereby inhibiting AXL signaling. |
| PC-38829 |
Lerodalcibep
Anti-PCSK9 fusion protein
|
LIB003 (Lerodalcibep) is an engineered PCSK9 protein inhibitor for the treatment of hypercholesterolemia. Anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type III domain, fused via peptidyl linker (97GSGSGS102) to human serum albumin (103-687), variant (C34>A136), produced in Chinese hamster ovary (CHO) cells. |
